Is Your NAD+ Supplement Working Hard — But Not Working Well?

Plenty of people take NAD+ supplements to feel sharper, stronger, and more resilient. But here’s the bit that doesn’t get talked about enough: if your body is stuck in a state of chronic inflammation, that NAD+ might be working flat out just to keep you going — instead of helping you thrive.

Let’s unpack that.

Where’s Your NAD+ Really Going?

When you’re dealing with ongoing stress, poor sleep, high sugar intake or environmental toxins, your cells switch into damage-control mode. Rather than fuelling your mitochondria — those tiny power stations in your cells — your body diverts NAD+ towards calming inflammation, supporting immune activity, and patching up damage.

So while your NAD+ is still pulling its weight, it’s not able to focus on what you actually want: better energy, better recovery, better health.

That’s why many people feel frustrated with their results. The NAD+ is helping, but your internal environment is working against it.

How to Get More From Your NAD+

If you want your NAD+ supplement to perform at its best, you need to give it the right setting to shine. That means taking steps to reduce the inflammation that’s stealing its attention in the first place.

Here are a few practical tips:

✅ Cut back on inflammatory triggers — processed sugars, broken sleep, and constant stress are all culprits. Prioritise good rest, and build in ways to manage stress, whether that’s breathwork, mindfulness, or simple movement.

✅ Eat more antioxidants — think berries, leafy greens, turmeric, oily fish. These foods help keep oxidative stress in check.

✅ Stack with glutathione — your body’s master antioxidant. Glutathione helps to neutralise oxidative stress and reduce inflammation at a cellular level, clearing the way so your mitochondria can focus on making energy.

Why Glutathione?

Glutathione is like the caretaker of your antioxidant defences, helping to tidy up free radicals, recycle other antioxidants, and support the liver’s detox pathways. Pairing it with NAD+ is a smart move: you clear the clutter first, so your NAD+ can get on with powering up your cells.

When your body isn’t constantly fighting fires, your mitochondria can do their proper job — keeping you energised, focused, and recovering well.

In short? If your NAD+ feels like it’s working but not delivering everything you hoped, take a step back and look at the whole picture. Lower the inflammation, support your antioxidant systems, and consider pairing NAD+ with glutathione to help your body get back to its best.